If weight/ease of portability is a requirement....

[Landon Johnson]

what guitar might be best for me? I'm an intermediate player and play out more than I play in... need a guitar I can toss in the car with a moment's notice and keep in the case otherwise.

I currently have a ProLite and a Williams S-10 Widebody. I'm thinking of picking up a road guitar that's just a single S-10 with a minimum of 3 and 4. The ProLite is a bit heavier and I don't really need the pad, and the Williams is far too pretty to go on the road... So far, I feel my choices are (as far as new guitars go):

Justice S-10 Pro
GFI Expo
Mullen Discovery
BMI Axius 2 (they discontinued their flight model?)

There are others but these seem to be the lightest out there... which would you choose, and why?

[Ken Pippus]

I picked up a GFI Ultra keyless S-10 for that exact concern. Lighter and smaller than all of the above.

I’d just play the Williams. My other grab’n’go is a keyless Williams D-10.

[Bruce Derr]

+1 for GFI Ultra S-10 keyless. I love mine. You could get a lightweight case to make it even lighter.

GFI used to show a lightweight fly-gig model on their website. It had a slightly shorter scale. Someone said recently that they will still make one by request, even though they are no longer advertised. It is not keyless, though. It's puzzling that nobody makes a lightweight travel-friendly guitar that is keyless. Some keyless tuners are only a couple inches long, which would shave significant weight and length from a keyed model. It would be great for a guitar designed for flight/subway dates. It might even fit in an overhead luggage compartment.

I should mention that I have not tried the other guitars in your list. I imagine you wouldn't go wrong with any of them.

[Justin Shaw]

I don't have experience with everything in the poll, but my Excel is super light and comes in a nice fitted flight case with wheels and everything. It's incredibly portable. I guess that's not news though.

[Steve Lipsey]

Williams S-10 Keyless - smaller and lighter, but zero sacrifices in tone or function, this is a total win. With a Hatton case, it is light, small, and a tone monster...(the Williams S-10 is less deep than a typical S-10, the legs are angled a bit more out to give the same stability)
And why wouldn't you take a pretty steel to a gig? It is pretty for the audience to see, right?